The goal is keeping you cancer free for as long as possible
Based on your answers, here is information about some treatment options after surgery.
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Prepare for a conversation with your doctor
Below are some starter questions to begin a conversation with your doctor or care team:
- Can we discuss my treatment goals?
- How might adjuvant treatment help me?
- How will you know if my treatment is working?
- What kind of side effects might I experience during adjuvant treatment?

After neoadjuvant treatment and surgery, continuing treatment can help lower the chance of your cancer coming back. Your doctor may recommend a targeted treatment for HER2+ eBC.
If your doctor recommends PERJETA + Herceptin after surgery

Treatment is 18 cycles in total. If you received PERJETA + Herceptin for 3-6 cycles before surgery, then you may continue the same drug for the remaining 12-15 cycles of treatment, unless the cancer comes back or side effects require the treatment to stop.
If your doctor recommends PHESGO after surgery

Treatment is 18 cycles in total. If you received PHESGO for 3-6 cycles before surgery, then you may continue the same drug for the remaining 12-15 cycles of treatment, unless the cancer comes back or side effects require the treatment to stop.
Discover study results with PHESGO
- See clinical trial results
- Find out if more people preferred PHESGO or PERJETA + Herceptin
Summarizing the key differences between these two treatments
PERJETA + Herceptin | PHESGO | |
---|---|---|
Active ingredients | pertuzumab trastuzumab | pertuzumab trastuzumab hyaluronidase |
Administration method | Intravenous (IV) infusion, given by a care provider | Subcutaneous (under the skin) injection, given by a care provider |
Administration time | About 1-2.5 hours*:
|
Your first dose is given in about 8 minutes. Other injections take about 5 minutes.* |
Study results summary | A study comparing PHESGO to PERJETA + Herceptin found no major difference is expected in how well PHESGO works. By taking PHESGO, you’re taking the same medicines, just in less time. There are side effects associated with both treatments. The comparison study did not find any significant difference between the 2 treatments. |
*This does not account for observation time and other aspects of treatment. Actual clinic time may vary.
Keep in mind that this site is for educational purposes only and that the options here are just some of the treatments you may be eligible for. Your primary sources of information should always be your doctor and the professionals who make up your care team. Only they can give you medical advice about your disease and treatment.